Outlook not working

Is there something going on with the hosted exchange server that Outlook won't connect?  We have several computers that have no issue logging in on the web client, but Outlook won't connect.  Everything was fine at the end of the day yesterday, today Outlook doesn't work.  I ran through all the settings and everything is correct.  Using the repair option in Outlook, it goes through auto discovery and says everything went fine, but when going back to Outlook, it says disconnected in the bottom right corner.  Any suggestions?

BLG